Litramine™'s mechanism of action is non-systemic

Litramine™’s insoluble and soluble fibres, their optimised particle size and ratio contribute to two main functional properties of Litramine™.

1. Dietary Fat Binding and Elimination

The fat binding mechanism of Litramine™ is contributed by the presence of insoluble and soluble fibres via a 2-step mechanism:

  1. Insoluble fibres
    The insoluble fibre fraction of Litramine™ binds to the dietary fats in the meal, in the upper part of the stomach through lipophilic interactions thus creating large fat-fibre complexes. This bond is pH independent.
  2. Soluble fibres
    The soluble fibres in Litramine™ are non-starch, mucilage type of polysaccharide, able to absorb water as they swell to form a stable fluid gel. This gel structure reinforces the fat-fibre complexes formed under the primary lipophilic interaction. The large fat-fibre complexes formed are protected from digestion and absorption, and are then excreted naturally from the body.

Due to reduced digestion and absorption of fats from food, lesser calories are available from dietary fats. By appropriate use of Litramine™, adjusted to the content of dietary fat anticipated, weight loss is achieved. When used in combination with a suitable diet and exercise plan, a negative calorie input-expenditure balance can be created for more effective weight loss.


2. Promotes a Feeling of Satiety

The insoluble fibres provide a bulking effect while the soluble fibres build up the viscosity in the gastrointestinal tract. Together, these actions impact gastric distension and gastric emptying that result in a feeling of satiety and fullness. In addition, consuming fibres help to balance the blood sugar levels, thereby helping to manage hunger and food cravings.

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Copyright © 2015 by InQpharm Group. All rights reserved. Last updated: Nov 2015 | ID: ML/TM/EN/15/001
Litramine and InQpharm are trademarks of the InQpharm group of companies.